Place the ground beef, bread crumbs, onion powder, garlic powder and parsley into a large mixing bowl and combine thoroughly.
Place the contents of the jar of sauce onto the bottom of the Instant Pot.
Form meatballs and place into the sauce.
Place the ziti into the Instant Pot.
Place the can of diced tomatoes and the water on top of the ziti.
Set the Instant Pot to manual 6 minutes.
When the Instant Pot is finished cooking, let sit for about 5 minutes then do a quick pressure release.
Serve as is or with some shredded cheese or grated cheese on top.